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XAV 939, Tocris Bioscience™
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Quantità:
10 mg
50 mg
Descrizione
XAV 939 is a potent tankyrase (TNKS) inhibitor (IC50 values are 4 and 11 nM for TNKS2 and TNKS1 respectively). Antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the β-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyocyte differentiation in mesoderm progenitor cells. Also used in neuronal differentiation protocols.
XAV 939 synthesized to cGMP guidelines also available.
For more information about how XAV 939 may be used, see our protocol: Accelerated Induction of Cortical Neurons from hiPSCs
Specifica
Materiale o nome chimico | XAV 939 |
Quantità | 10 mg |
Peso formulazione | 312.31 |
Percent Purity | >98% |
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