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Thermo Scientific Essential Chemicals for Biosynthesis: Oligonucleotides and Peptides

It’s the peace of mind that comes with a consultative, effective and service-focused team, beyond chemistry.


Overview


Essential Chemicals for Biosynthesis: Oligonucleotides and Peptides

We offer essential chemicals needed to support the synthesis and purification of oligonucleotides and peptides, both in catalog and bulk formats. These include:

  • Solvents (including extra-dry, peptide synthesis grade, HPLC grade, LC-MS grade, and ACS grade)
  • Reagents (coupling, protection, deprotection, and deblocking agents)
  • Capping reagents (CAP A and CAP B)
  • Activators and oxidizers

Custom and Bulk Service Solutions

We understand that every biosynthesis customer is different.
Whether you're engaged in research, scale-up, or production, our customizable chemicals and chemical blends are formulated to your precise requirements. Working with our team of experts, our service is tailored to meet your exact specifications.

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Bulk/High-Volume Services

High-Volume Solvents and Blends​

Improve efficiency and safety with environmentally conscious high-volume solvent delivery services. Explore a range of grades, volumes, and container options to suit your analytical and manufacturing requirements.

Large-Quantity Chemical Offerings

Order a wide variety of catalog chemicals in larger sizes and formats. These chemicals can be tested, packaged, and delivered to your specifications.

Bulk/High-Volume Services

Custom Chemicals Services

Custom Blends and Synthesis

Access an extensive database of production methods for over 8,000 compounds developed through 50 years of experience in custom manufacturing.

Custom Pack Size, Specification, Packaging, and Labels

Improve handling, storage, and product integrity by choosing the exact material, weight, and packaging to meet your specifications.​

Custom Chemicals Services

Why Choose Thermo Fisher Scientific for your Bulk and Custom Chemicals?

High Purity and Range

Our curated list of chemicals and chemical blends contains high-purity solvents and reagents for all synthesis and purification stages – with options for greener alternatives.

Sustainability

Our returnable container/drum service reduces waste and disposal costs, with cleaning and refilling services to minimize hazardous disposal needs.

Partnership

We provide extensive technical support and resources for optimizing synthesis protocols, backed by strong partnerships and expertise.

Quality and Compliance

We offer compliance-ready specifications with full traceability and documentation, adhering to the stringent quality control requirements in ISO-9001 facilities, including custom QC and validation samples.

Global Supply

Our global network ensures efficient logistics and quick delivery, supported by dedicated teams for fleet management.

Oligonucleotide Synthesis


Whether you're engaged in research or scaling up for production, count on Thermo Fisher Scientific customizable chemicals and blends for your oligonucleotide synthesis. With over 65 years of experience in chemical manufacturing, Thermo Fisher Scientific offers 92,000+ chemicals through an extensive global network of 3,500+ manufacturers. Trust their expert team to tailor your order to meet your exact specifications and deliver it to your location by the date you need it.


A Reliable Service That Meets Your High Standards

Rely on Thermo Fisher Scientific to support your bench-to-production oligonucleotide applications. Once the team establishes your chemical needs, they will manufacture the high-purity, high-yield products you require to optimize your results, including:

  • Activators
  • CAP A and CAP B solutions
  • Deblocking agents
  • Extra-dry solvents
  • Oxidizers

Your Own Fleet

Dedicated fleet.

Production

Scalable

Logistics and warehousing.

World

One Call/Email

Easy access to your fleet.

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Sustainable

>90kg (200 lb) of cardboard and glass eliminated per drum.

Recycle

To precisely meet your specifications and deliver your chemicals as promised while helping to protect the environment, Thermo Fisher Scientific abides by these four operational pillars:

Sustainability

You can help meet your sustainability goals and protect the environment by taking advantage of the Thermo Fisher Scientific returnable container service, which reduces the amount of glass and cardboard you need to dispose of. For example, with each 200L returnable container, you can eliminate almost 90kg (200 lb) of glass and cardboard waste.

The returnable container program dedicates a fleet of drums and/or barrels to your chemicals so you can rest assured your order won’t be exposed to cross-contamination. This service also includes the cleaning, maintaining, and refilling of your empty drums/barrels, which can not only reduce your hazardous disposal costs, but can also eliminate the need for rinsing at your site.

The program works like this: After you place your order, your chemicals are manufactured then delivered to you in a reusable container. Once you have emptied the container, you can arrange a time for Thermo Fisher Scientific to pick it up. The drum/barrel then gets cleaned, validated, and refilled for shipment back to you.

Quality and Compliance

Through the custom oligonucleotide synthesis service, Thermo Fisher Scientific produces compliance-ready products, which are fully traceable and come with complete documentation. They are manufactured in a world-class ISO-9001 facility using a strict quality control process.

Custom quality control is available and you may also request lot validation samples. To help ensure there is no potential for cross-contamination, your chemicals will be packaged in a fleet of returnable containers that will be designated for your use only.

Global Supply

Dedicated Thermo Fisher Scientific teams are committed to meeting your precise requirements across continents. This includes supporting logistics, transportation, and container fleet management to maximize efficiency. Products are distributed through a global network of warehouses and can be delivered to you quickly, whenever and wherever you need them.

Partnership

As your partner, Thermo Fisher Scientific believes in maintaining clear and open lines of communication in order to manage projects effectively. A dedicated team will consult with you about your needs and offer technical expertise when necessary, supporting you throughout the entire order and fulfilment process.


A Reliable Service That Meets Your High Standards

Peptide Synthesis


The go-to chemicals provider for peptide synthesis customers involved in standard and greener syntheses. 

We offer both catalog and “custom and bulk” chemicals options in a variety of grades to support both peptide synthesis and purification. 


Solvents for Reaction, Washing and Purification

Solvents are critical in peptide synthesis, serving as the medium in which reactions occur and impacting both the efficiency of the synthetic process and the purity of the product. Recently, there has been increased interest in finding alternative, greener solvents to support peptide synthesis.

If you are interested in alternative solvent options (or blends of solvents), then why not reach out to learn more about our custom and bulk chemicals program.



Coupling, Protection, and Deprotection Reagents

Coupling, protection, and deprotection reagents play crucial roles in ensuring the correct sequence and structure of the peptide chain. These reagents collectively contribute to the precision and efficiency of peptide synthesis.

Learn More About Our Peptide Reagents Range: 


Thermo Fisher Scientific Peptide Synthesis Chemicals Benefits

With our catalog products and custom/bulk chemical services, we aim to support efficient, reliable, and high-quality peptide synthesis for various applications in research and industry. Benefits of our offering include:

  1. High purity and wide range: Our chemicals are of high purity, ensuring the synthesis of peptides with high fidelity and performance. We provide a comprehensive range of solvents (for reaction, washing, and purification), as well as coupling, protection and deprotection reagents, and amino acids suitable for all stages of peptide synthesis (whether you use more popular reagents and solvents, or are looking for a greener alternative).
  2. Consistency and efficiency: Our chemicals are manufactured to deliver consistent results across different batches, which helps optimize the synthetic process, reduce reaction times, and improve yields, crucial for reproducibility in research and production. Our products are all manufactured in world-class ISO-9001 facilities.
  3. Compatibility and scalability: Our chemicals are compatible with automated peptide synthesizers, enhancing workflow efficiency. They are also suitable for both small-scale research applications (catalog products) and large-scale industrial production (custom and bulk services).

Technical Support: Thermo Scientific offers excellent technical support and resources to help troubleshoot and optimize peptide synthesis protocols. Our teams have a proven track record of cultivating robust partnerships, offering technical expertise, providing valuable consultation, managing projects effectively, and maintaining clear and open lines of communication.

Contact Us


If you’re looking for a partner to connect you with the right chemicals and blends for oligonucleotide and/or peptide synthesis, let Thermo Fisher Scientific support your project. Their extensive knowledge has been developed and cultivated through 50 years of experience in custom manufacturing.

Contact Us