CAS RN 942183-80-4

IUPAC Nome: 1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide

Sinonimi: 1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide

Peso molecolare (g/mol): 587.69

Formula molecolare: C33H33N9O2

InChi Key: HDAJDNHIBCDLQF-UHFFFAOYNA-N

SMILES: O=C(CN1CCC(C1)C(=O)NC1=CC=C2NN=C(C2=C1)C1=CC=NC=C1)N1CCN(CC1)C1=CC=C(C=C1)C1=NC=CC=N1

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Thermo Scientific Chemicals SCH772984, 95%

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SCH772984, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Prezzi e disponibilità

SCH772984, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Prezzi e disponibilità

MedChemExpress SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-naïve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations.

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Specifiche

Peso formulazione	587.67
Note sul grado di purezza	Research
Colore	Yellow
Forma fisica	Solid
Molecular Weight (g/mol)	587.67
Conservazione consigliata	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMILES	O=C([C@H](CC1)CN1CC(N(CC2)CCN2C(C=C3)=CC=C3C4=NC=CC=N4)=O)NC5=CC6=C(C=C5)NN=C6C7=CC=NC=C7
Durata utile	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula molecolare	C₃₃H₃₃N₉O₂
Percent Purity	98.69%
Informazioni di solubilità	DMSO : 48 mg/mL (81.68 mM; Need ultrasonic)
CAS	942183-80-4
Da utilizzare con (applicazione)	Cancer-Kinase/protease
Materiale o nome chimico	SCH772984
Grado	Research

CAS RN 942183-80-4

CAS RN 942183-80-4

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