CAS RN 950769-58-1

IUPAC Nome: —

Sinonimi: —

Peso molecolare (g/mol): —

Formula molecolare: —

InChi Key: —

SMILES: —

1 – 2 di 2 risultati

AC 220, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Prezzi e disponibilità

MedChemExpress Quizartinib (AC220) is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a Kd of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC50s of 4.2 and 1.1 nM, respectively. Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib induces apoptosis.

Prezzi e disponibilità
Specifiche

Peso formulazione	560.67
Sinonimo	AC220
Note sul grado di purezza	Research
Colore	Off-White
Forma fisica	Solid
Molecular Weight (g/mol)	560.67
Conservazione consigliata	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMILES	O=C(NC1=NOC(C(C)(C)C)=C1)NC2=CC=C(C=C2)C3=CN4C(SC5=CC(OCCN6CCOCC6)=CC=C45)=N3
Durata utile	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula molecolare	C₂₉H₃₂N₆O₄S
Percent Purity	98.87%
Informazioni di solubilità	DMSO : ≥ 33 mg/mL (58.86 mM)
CAS	950769-58-1
Da utilizzare con (applicazione)	Cancer-Kinase/protease
Materiale o nome chimico	Quizartinib
Grado	Research

CAS RN 950769-58-1

CAS RN 950769-58-1

Risultati della ricerca filtrata

Filtra risultati