CAS RN 960374-59-8

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ONX 0914, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

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ONX 0914, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Prezzi e disponibilità

ONX 0914, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Prezzi e disponibilità

MedChemExpress ONX-0914 (PR-957) is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 μM). ONX-0914 reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1.

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Specifiche

Peso formulazione	580.67
Sinonimo	PR-957
Note sul grado di purezza	Research
Colore	White
Forma fisica	Solid
Molecular Weight (g/mol)	580.67
Conservazione consigliata	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
SMILES	O=C(N[C@@H](C)C(N[C@@H](CC1=CC=C(OC)C=C1)C(N[C@@H](CC2=CC=CC=C2)C([C@]3(C)OC3)=O)=O)=O)CN4CCOCC4
Durata utile	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula molecolare	C₃₁H₄₀N₄O₇
Percent Purity	95.03%
Informazioni di solubilità	DMSO : ≥ 35 mg/mL (60.28 mM)
CAS	960374-59-8
Da utilizzare con (applicazione)	COVID-19-immunoregulation
Materiale o nome chimico	ONX-0914
Grado	Research

CAS RN 960374-59-8

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