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1-Methylpiperazine, 98+%

Codice prodotto. 11429802
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Codice prodotto. 11429802 Fornitore Thermo Scientific Alfa Aesar N. del fornitore A10837.AE
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Descrizione

CAS: 109-01-3 | C5H12N2 | 100.165 g/mol

1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

Solubility
Miscible with water and methanol.

Notes
Hygroscopic. Moisture sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 109-01-3
Formula molecolare C5H12N2
Molecular Weight (g/mol) 100.165
Numero MDL MFCD00005966
InChI Key PVOAHINGSUIXLS-UHFFFAOYSA-N
Sinonimo n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine
PubChem CID 53167
IUPAC Name 1-methylpiperazine
SMILES CN1CCNCC1

Specifications

Materiale o nome chimico 1-Methylpiperazine
Punto di fusione -6°C
Densità 0.903
Punti di ebollizione 137°C to 139°C
Punto d'infiammabilità 34°C (93°F)
Odore Amine-like
Indice di rifrazione 1.4655
Quantità 100 mL
Numero UN UN2734
Beilstein 102724
Sensibilità Air Sensitive
Informazioni di solubilità Miscible with water and methanol.
Peso formulazione 100.17
Percent Purity ≥98%
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Safety and Handling

compliance-icons compliance-icons compliance-icons
Product Identifier
  • 1-Methylpiperazine
 Signal Word
  • Pericolo
 Hazard Category
  • Tossicità acuta Categoria 4
  • Lesione oculare grave/irritazione oculare Categoria 1
  • Liquido infiammabile Categoria 3
  • Corrosione/irritazione della pelle Categoria 1B
 Hazard Statement
  • H226-Liquido e vapori infiammabili.
  • H312-Nocivo per contatto con la pelle.
  • H314-Provoca gravi ustioni cutanee e gravi lesioni oculari.
  • H318-Provoca gravi lesioni oculari.
  • H332-Nocivo se inalato.
 Precautionary Statement
  • P210-Tenere lontano da fonti di calore, superfici riscaldate, scintille, fiamme e altre fonti di innesco. Vietato fumare.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
  • P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
  • P310-Contattare immediatamente un CENTRO ANTIVELENI/un medico .
 Supplemental information
  • MIXTURE LIST-Contiene: 1-Methylpiperazine
SDS

RUO – Research Use Only

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