Learn More
2,2,2-Trifluoroethanol, 99+%
Description
Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.
Solubility
Miscible with water, ethers, ketones, alcohols and chloroform.
Notes
Moisture sensitive.
Specifications
Specifications
| Materiale o nome chimico | 2,2,2-Trifluoroethanol |
| Punto di fusione | -44°C |
| Densità | 1.391 |
| Punti di ebollizione | 74°C to 75°C |
| Punto d'infiammabilità | 29°C (84°F) |
| Formula lineare | CF3CH2OH |
| Indice di rifrazione | 1.29 |
| Quantità | 500 g |
| Numero UN | UN1992 |
| Beilstein | 1733203 |
| Show More |
Safety and Handling
- 2,2,2-Trifluoroethanol
- Pericolo
- Tossicità acuta Categoria 3
- Lesione oculare grave/irritazione oculare Categoria 1
- Liquido infiammabile Categoria 3
- Tossicità per la riproduzione Categoria 1B
- Tossicità specifica per organi bersaglio (esposizione ripetuta) Categoria 2
- H226-Liquido e vapori infiammabili.
- H301-Tossico se ingerito.
- H318-Provoca gravi lesioni oculari.
- H331-Tossico se inalato.
- H360F-Può nuocere alla fertilità.
- H373-Può provocare danni agli organi.
- P210-Tenere lontano da fonti di calore, superfici riscaldate, scintille, fiamme e altre fonti di innesco. Vietato fumare.
- P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
- P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
- P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
- P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
- P310-Contattare immediatamente un CENTRO ANTIVELENI/un medico .
- MIXTURE LIST-Contiene: 2,2,2-Trifluoroethanol
RUO – Research Use Only
Your input is important to us. Please complete this form to provide feedback related to the content on this product.