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  8. 2-Iodoacetamide, 98%, stab. with ca 5-8% water

2-Iodoacetamide, 98%, stab. with ca 5-8% water

Codice prodotto. 11467736
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Codice prodotto. 11467736 Fornitore Thermo Scientific Alfa Aesar N. del fornitore A14715.06
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Descrizione

CAS: 144-48-9 | C2H4INO | 184.964 g/mol

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Solubility
Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

Notes
Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 144-48-9
Formula molecolare C2H4INO
Molecular Weight (g/mol) 184.964
Numero MDL MFCD00008028
InChI Key PGLTVOMIXTUURA-UHFFFAOYSA-N
Sinonimo iodoacetamide, monoiodoacetamide, surauto, acetamide, 2-iodo, 2-iodo-acetamide, usaf d-1, alpha-iodoacetamide, ccris 7710, unii-zrh8m27s79, n-3-methoxy-4-butoxybenzyl thiobarbituric acid
PubChem CID 3727
IUPAC Name 2-iodoacetamide
SMILES C(C(=O)N)I

Specifica

Materiale o nome chimico Iodoacetamide
Nota nome stabilized with ≈5 to 8% water
Punto di fusione 92°C to 95°(dried)
Intervallo percentuale saggio 98%, stabilized with ca 5% water
Quantità 5 g
Numero UN UN2811
Beilstein 1739080
Sensibilità Light sensitive
Informazioni di solubilità Soluble in water,dimethyl formamide and ethanol. Slightly soluble in methanol.
Peso formulazione 184.96
Percent Purity 98%
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RUO – Research Use Only

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