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  7. 2-Methoxyethoxymethyl chloride, 94%

2-Methoxyethoxymethyl chloride, 94%

Codice prodotto. 11384424
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11384424 5 g 5g
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Codice prodotto. 11384424 Fornitore Thermo Scientific Alfa Aesar N. del fornitore L01050.06
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Descrizione

CAS: 3970-21-6 | C4H9ClO2 | 124.56 g/mol

2-Methoxyethoxymethyl chloride, is used as selectively cleaved under aprotic conditions in the presence of a wide range of OH-protected reagents. It is used as an OH-protecting reagent. An examples of the target molecule MEM Chloride is the side chain of roxithromycin. It is also used in the protection of the OH groups in serine and threonine during peptide synthesis. Some of the other applications include have the ability to coordinate to metals, which is thought to accelerate the cleavage by Lewis acids. The chelating ability of the MEM ether also makes it useful as a stereodirecting group in organometallic reactions, first noted in the stereo controlled addition of ?-methoxyvinyllithium to a carbonyl in the synthesis of taxusin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Methoxyethoxymethyl chloride, is used as selectively cleaved under aprotic conditions in the presence of a wide range of OH-protected reagents. It is used as an OH-protecting reagent. An examples of the target molecule MEM Chloride is the side chain of roxithromycin. It is also used in the protection of the OH groups in serine and threonine during peptide synthesis. Some of the other applications include have the ability to coordinate to metals, which is thought to accelerate the cleavage by Lewis acids. The chelating ability of the MEM ether also makes it useful as a stereodirecting group in organometallic reactions, first noted in the stereo controlled addition of ɑ-methoxyvinyllithium to a carbonyl in the synthesis of taxusin.

Solubility
It hydrolyzes with water.

Notes
Moisture, Heat, water Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.
TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 3970-21-6
Formula molecolare C4H9ClO2
Molecular Weight (g/mol) 124.56
Numero MDL MFCD00000888
InChI Key BIAAQBNMRITRDV-UHFFFAOYSA-N
Sinonimo 2-methoxyethoxymethyl chloride, 1-chloromethoxy-2-methoxyethane, ethane, 1-chloromethoxy-2-methoxy, mem chloride, methoxyethoxymethyl chloride, mem-chloride, 1-chloro-2,5-dioxahexane, 2-methoxyethoxy methyl chloride, beta-methoxyethoxymethyl chloride, .beta.-methoxyethoxymethyl chloride
PubChem CID 77590
IUPAC Name 1-(chloromethoxy)-2-methoxyethane
SMILES COCCOCCl

Especificaciones

Materiale o nome chimico 2-Methoxyethoxymethyl chloride
Densità 1.094
Punti di ebollizione 50°C to 52°C (13 mmHg)
Punto d'infiammabilità 54°C (129°F)
Formula lineare CH3O(CH2)2OCH2Cl
Indice di rifrazione 1.427
Quantità 5 g
Numero UN UN1992
Beilstein 1900576
Sensibilità Moisture sensitive
Informazioni di solubilità It hydrolyzes with water.
Peso formulazione 124.57
Percent Purity 94%
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RUO – Research Use Only

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