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  8. 3,3',5,5'-Tetramethylbenzidine soln., Ready-to-Use, high sensitivity, Thermo Scientific Chemicals

3,3',5,5'-Tetramethylbenzidine soln., Ready-to-Use, high sensitivity, Thermo Scientific Chemicals

Codice prodotto. 15420187
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Codice prodotto. 15420187 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J61325.=E
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Descrizione

3,3’,5,5’-Tetramethylbenzidine (TMB, CAS # 54827-17-7) is a blue chromogenic substance used in staining techniques such as immunohistochemistry.

TMB is a substrate for horseradish peroxidase. Recommended for ELISA (microwell) procedures,3,3?,5,5?-Tetramethylbenzidine has been used in a study to demonstrate that by measuring substrate absorption values off the absorption maximum, the measuring range of any immunoenzymometric assay can be extended significantly without jeopardizing assay characteristics. 3,3?,5,5?-Tetramethylbenzidine has also been used in a study to understand the formation of CuS concave superstructures with peroxidase-like activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• TMB is an aromatic amine that acts as a hydrogen donor in horseradish peroxidase-catalyzed reactions
• The transfer of hydrogen results in a blue stain associated with the target of interest
• This pH-dependent color change can be confirmed using spectrophotometric methods
• TMB is commonly used in immunohistochemistry; TMB is light-sensitive, and all applications should be performed in the dark

Application

• TMB is suitable for immunohistochemistry and immunocytochemistry applications including ELISA and cell and tissue staining

TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 54827-17-7
Formula molecolare C16H20N2
Molecular Weight (g/mol) 240.35
Numero MDL MFCD00007748
InChI Key UAIUNKRWKOVEES-UHFFFAOYSA-N
Sinonimo 3,3',5,5'-tetramethylbenzidine, 3,3',5,5'-tetramethyl-1,1'-biphenyl-4,4'-diamine, 3,5,3',5'-tetramethylbenzidine, tmb, 3,3',5,5'-tetramethyl benzidine, tmb substrate, bm blue, ccris 4727, tmb plus, tmb, insoluble
PubChem CID 41206
IUPAC Name 4-(4-amino-3,5-dimethylphenyl)-2,6-dimethylaniline
SMILES CC1=CC(=CC(=C1N)C)C2=CC(=C(C(=C2)C)N)C

Specifications

Materiale o nome chimico 3,3',5,5'-Tetramethylbenzidine soln.
Nota nome Ready-to-Use, high sensitivity
Colore Yellow
Quantità 125 mL
Numero UN UN2810
Beilstein 2808541
Informazioni di solubilità Insoluble in water. Soluble in organic solvents such as DMSO,96 % Ethanol,Acetone,Chloroform,Toluene.
Peso formulazione 240.35
Forma fisica Liquid

Safety and Handling

compliance-icons compliance-icons compliance-icons
Product Identifier
  • 3,3',5,5'-Tetramethylbenzidine solution, Ready-to-Use, high sensitivity
 Signal Word
  • Pericolo
 Hazard Category
  • Tossicità acuta Categoria 3
  • Tossicità acuta Categoria 4
  • Liquido infiammabile Categoria 3
  • Tossicità specifica per organi bersaglio (esposizione singola) Categoria 1
 Hazard Statement
  • H226-Liquido e vapori infiammabili.
  • H302-Nocivo se ingerito.
  • H312-Nocivo per contatto con la pelle.
  • H331-Tossico se inalato.
  • H370-Provoca danni agli organi.
  • EUH066-L'esposizione ripetuta può provocare secchezza o screpolature della pelle.
 Precautionary Statement
  • P210-Tenere lontano da fonti di calore, superfici riscaldate, scintille, fiamme e altre fonti di innesco. Vietato fumare.
  • P264-Lavare accuratamente dopo l'uso.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
  • P303+P361+P353-IN CASO DI CONTATTO CON LA PELLE (o con i capelli): togliere immediatamente tutti gli indumenti contaminati. Sciacquare la pelle/fare una doccia.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.
  • P311-Contattare un CENTRO ANTIVELENI/un medico/ .
 Supplemental information
  • MIXTURE LIST-Contain: Methanol, Acetone, Hydrogen peroxide
SDS

RUO – Research Use Only

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