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3,3',5-Triiodo-L-thyronine, 95%
Descrizione
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3', 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3', 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3'-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3?,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3′, 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3′, 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3′-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3′,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.
Solubility
Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.
Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, Strong bases, light.
Specifica
Specifica
| Materiale o nome chimico | 3,3',5-Triiodo-L-thyronine |
| Punto di fusione | 234°C to 238°C |
| Quantità | 1 g |
| Sensibilità | Light sensitive |
| Informazioni di solubilità | Insoluble in water,ethanol and propylene glycol. Soluble in dilute alkalies. |
| Optical Rotation | +25° (c=1 in 1M HCl/Ethanol 1:2) |
| Peso formulazione | 650.97 |
| Percent Purity | 95% |
Sicurezza e movimentazione
- 3,3',5-Triiodo-L-thyronine
- Attenzione
- Lesione oculare grave/irritazione oculare Categoria 2
- Corrosione/irritazione della pelle Categoria 2
- Tossicità specifica per organi bersaglio (esposizione singola) Categoria 3
- H315-Provoca irritazione cutanea.
- H319-Provoca grave irritazione oculare.
- H335-Può irritare le vie respiratorie.
- P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
- P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
- P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
- P312-Contattare un CENTRO ANTIVELENI/un medico/in caso di malessere.
- P332+P313-In caso di irritazione della pelle: consultare un medico.
- P337+P313-Se l'irritazione degli occhi persiste, consultare un medico.
- MIXTURE LIST-Contain: Liothyronine
RUO – Research Use Only
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