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4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%, Thermo Scientific Chemicals
Descrizione
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
Solubility
Soluble in water 50 mg/mL or 100% ethanol.
Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.
Specifica
| Materiale o nome chimico | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride |
| Punto di fusione | ∼184°C (decomposition) |
| Quantità | 250 mg |
| Numero UN | UN3261 |
| Beilstein | 7604627 |
| Sensibilità | Moisture sensitive |
| Informazioni di solubilità | Soluble in water 50mg/mL or 100% ethanol. |
| Peso formulazione | 239.69 |
| Percent Purity | 97% |
RUO – Research Use Only