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5-Bromo-2'-deoxyuridine, 99%

Codice prodotto. 15443647
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Quantità:
250 mg
1 g
5 g
Dimensione della confezione:
1g
250mg
5g
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15443647 250 mg 250mg
11322289 1 g 1g
11332289 5 g 5g
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Codice prodotto. 15443647 Fornitore Thermo Scientific Alfa Aesar N. del fornitore H27260.MD
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CAS: 59-14-3 | C9H11BrN2O5 | 307.10 g/mol

5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 59-14-3
Formula molecolare C9H11BrN2O5
Molecular Weight (g/mol) 307.10
Numero MDL MFCD00006529
InChI Key WOVKYSAHUYNSMH-RRKCRQDMSA-N
Sinonimo 5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
PubChem CID 6035
ChEBI CHEBI:472552
IUPAC Name 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
SMILES OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O

Specifica

Materiale o nome chimico 5-Bromo-2'-deoxyuridine
Punto di fusione ∽190°C (decomposition)
Quantità 250 mg
Beilstein 30395
Indice di Merck 14,1452
Informazioni di solubilità Soluble in water.
Optical Rotation +31° (c=1 in 0.1N HCl)
Peso formulazione 307.1
Percent Purity 99%

RUO – Research Use Only

Titolo del prodotto
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