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Tocris Bioscience™ Ac-Cys-NHMe
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Codice prodotto. 30000012
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10 mg
50 mg
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Codice prodotto. Quantità unitSize
30000012 10 mg 10mg
30000025 50 mg 50mg
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Codice prodotto. 30000012 Fornitore Tocris Bioscience™ N. del fornitore 7936/10

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Building block for the lysine acylation using conjugating enzymes (LACE) technique

Ac-Cys-NHMe is a non-canonical amino acid that is an essential building block for lysine acylation using conjugating enzymes (LACE) technique. LACE is a chemoenzymatic approach that uses an E2 small ubiquitin-like modifier (SUMO)-conjugating enzyme, Ubc9, to conjugate peptide thioesters containing a C-terminal ubiquitin-derived sequence (LRLRGG) to a lysine residue located in a recognition sequence (IKQE) on a protein via an isopeptide bond. Ac-Cys-NHMe can be reacted with a peptide hydrazide to form a reactive peptide thioester, which is the substrate for Ubc9. LACE enables the site-specific modification of proteins at lysine residues to allow attachment of biochemical probes such as fluorophores to proteins or to engineer proteins for site-specific delivery.
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Specifica

Materiale o nome chimico (2R)-2-(Acetylamino)-3-mercapto-N-methylpropanamide
CAS 10061-65-1
Quantità 10 mg
Bersaglio Unnatural Amino Acids
Formula molecolare C6H12N2O2S
Titolo del prodotto
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