missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. 15452969

Actinomycin D

Codice prodotto. 15452969
Cambia vista
Click to view available options
Quantità:
5 mg
Dimensione della confezione:
5mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Codice prodotto. Quantità Dimensione della confezione
15452969 5 mg 5mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Codice prodotto. 15452969 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J60148.#0
 Articolo soggetto a restrizioni
In stock
Add to basket

missing translation for 'validMainframeMsg'

This item is not returnable. View return policy

Description

CAS: 50-76-0 | C62H86N12O16 | 1255.438 g/mol

Actinomycin D is used as an anti-neoplastic antibiotic. It is also used to inhibit RNA polymerase and is a potent inducer of apoptosis. It is also used as a potent antibiotic that binds to the GpC steps of DNA. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Actinomycin D is used as an anti-neoplastic antibiotic. It is also used to inhibit RNA polymerase and is a potent inducer of apoptosis. It is also used as a potent antibiotic that binds to the GpC steps of DNA. Inhibits DNA-primed R
TRUSTED_SUSTAINABILITY

Specifications

Materiale o nome chimico Actinomycin D
Tipo Actinomycin D
Forma fisica Powder
CAS 50-76-0
Punto di fusione 251°C to 253°C
Colore Orange to Red
Quantità 5 mg
Formula molecolare C62H86N12O16
Numero MDL MFCD00005033
Numero UN UN3462
Beilstein 605235
Indice di Merck 14,2800
Sinonimo Dactinomycin; Actinomycin C1
Informazioni di solubilità It is soluble ino 50 mM in DMSO.
InChI Key RJURFGZVJUQBHK-HUZQGMAJSA-N
SMILES CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
IUPAC Name 2-amino-4,6-dimethyl-3-oxo-1-N-[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]-9-N-[(3R,6S,7R,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,
Molecular Weight (g/mol) 1255.438
PubChem CID 131954673
Peso formulazione 1255.4
Show More Show Less

Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • Actinomycin D
 Signal Word
  • Pericolo
 Hazard Category
  • Tossicità acuta Categoria 2
  • cancerogenicità Categoria 1A
  • Tossicità per la riproduzione Categoria 1A
 Hazard Statement
  • H300-Letale se ingerito.
  • H350-Può provocare il cancro.
  • H360-Può nuocere alla fertilità o al feto.
 Precautionary Statement
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P264-Lavare accuratamente dopo l'uso.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.
  • P405-Conservare sotto chiave.
 Supplemental information
  • MIXTURE LIST-Contain: Actinomycin D
SDS

RUO – Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.