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  7. Alendronate sodium trihydrate, 97%

Alendronate sodium trihydrate, 97%

Codice prodotto. 15493999
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5 g
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15493999 1 g 1g
15404009 5 g 5g
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Codice prodotto. 15493999 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J61397.03
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Descrizione

CAS: 121268-17-5 | C4H18NNaO10P2 | 325.122 g/mol

Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.

Solubility
Soluble in water at 10mg/ml

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 121268-17-5
Formula molecolare C4H18NNaO10P2
Molecular Weight (g/mol) 325.122
Numero MDL MFCD01748233
InChI Key DCSBSVSZJRSITC-UHFFFAOYSA-M
Sinonimo alendronate sodium hydrate, alendronate sodium trihydrate, alendronate sodium, alendronate monosodium trihydrate, alendros, adronat, fosamax, sodium alendronate hydrate, elandor, fosalan
PubChem CID 23681107
ChEBI CHEBI:2566
IUPAC Name sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate
SMILES C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]

Specifica

Materiale o nome chimico Alendronate sodium trihydrate
Colore White
Quantità 1 g
Indice di Merck 14,229
Informazioni di solubilità Soluble in water at 10mg/ml
Peso formulazione 325.12 (271.08 Anhydrous)
Percent Purity 97%
Forma fisica Solid

RUO – Research Use Only

Titolo del prodotto
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