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  7. Amlodipine besylate, 98+%

Amlodipine besylate, 98+%

Codice prodotto. 15474589
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25 g
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25g
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Codice prodotto. 15474589 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J62164.14
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Descrizione

An L-type calcium channel antagonist with potent antioxidant activity | CAS: 111470-99-6 | C26H31ClN2O8S | 567.05 g/mol

Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.

Solubility
Soluble in DMSO (≥20 mg/mL), water (10 mM), chloroform, ethanol (≥14 mg/mL), and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 111470-99-6
Formula molecolare C26H31ClN2O8S
Molecular Weight (g/mol) 567.05
Numero MDL MFCD00887594
InChI Key ZPBWCRDSRKPIDG-UHFFFAOYSA-N
Sinonimo amlodipine besylate, amlodipine besilate, cardiorex, amlodipine benzenesulfonate, istin, amdepin, amdipin, amlodin, amlogard, amlopin
PubChem CID 60496
ChEBI CHEBI:2669
IUPAC Name benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

Specifica

Materiale o nome chimico Amlodipine besylate
Punto di fusione 195°C to 204°C
Colore White
Quantità 25 g
Indice di Merck 14,491
Informazioni di solubilità Soluble in DMSO (?20mg/mL),water (10 mM),chloroform,ethanol (?14mg/mL),and methanol.
Peso formulazione 567.05
Percent Purity ≥98%
Forma fisica Solid

RUO – Research Use Only

Titolo del prodotto
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