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CD71 Mouse anti-Human, Unlabeled, Clone: M-A712, BD

Codice prodotto. 15838248
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0.1 mg
Dimensione della confezione:
Pezzo
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Codice prodotto. Quantità unitSize
15838248 0.1 mg Pezzo
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Codice prodotto. 15838248 Fornitore BD Biosciences N. del fornitore 555534

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Mouse Monoclonal Antibody

The M-A712 monoclonal antibody specifically binds to CD71 which is also known as the transferrin receptor (TFR). This type II transmembrane glycoprotein is expressed on cells as a disulfide-linked homodimer comprised of 95 kDa monomers. CD71 is expressed on activated lymphocytes, monocytes, macrophages, erythroid progenitors, brain endothelium, and most proliferating cells. CD71 is not expressed on resting lymphocytes and is upregulated during lymphocyte responses to antigens or mitogens. Through an endocytic pathway, the transferrin receptor mediates cellular iron uptake by binding and internalizing iron that is bound to transferrin. After releasing iron within the low pH endosomal environment, transferrin and its receptor can be recycled to the cell surface.

TRUSTED_SUSTAINABILITY

Specifica

Antigene CD71
Applicazioni Flow Cytometry
Classificazione Monoclonal
Clone M-A712
Concentrazione 0.5mg/mL
Coniugato Unconjugated
Descrizione TFR; TFRC; Trfr; TfR1; Transferrin receptor protein 1
Formulazione Aqueous buffered solution containing ≤0.09% sodium azide.
Specie ospite Mouse
Immunogeno T-CLL and Jurkat Cells
Metodo di purificazione Affinity Purified
Quantità 0.1 mg
Status giuridico RUO
Disciplina di ricerca Immunology
Primario o secondario Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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For Research Use Only.

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