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anti-NFKBIB Matched Antibody Pair, Abnova
Descrizione
Includes
Rabbit MaxPab™ affinity purified polyclonal anti-NFKBIB (100μg); Mouse monoclonal anti-NFKBIB, IgG2aκ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-κ-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-κ-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-κ-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-κ-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at κ-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
ELISA
Specifica
Specifica
| Antigene | NFKBIB |
| Applicazioni | ELISA |
| Classificazione | Monoclonal/Polyclonal |
| Coniugato | Unconjugated |
| Descrizione | This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NFKBIB. |
| Gene | NFKBIB |
| Alias gene | IKBB/TRIP9 |
| Simboli geni | NFKBIB |
| Specie ospite | Mouse, Rabbit |
| Metodo di purificazione | Affinity Purified |
| Vedi altri risultati |
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