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Ascomycin, 95%

Codice prodotto. 15488229
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15488229 100 mg 100mg
15478229 25 mg 25mg
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Codice prodotto. 15488229 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J66751.MC
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Descrizione

Internal standard for LC-MS/MS testing of the immunosuppressants tacrolimus, sirolimus, and everolimus. | CAS: 104987-12-4 | C43H69NO12 | 792.02 g/mol

Ascomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases. Ascomycin is an inhibitor of PP2. It is an internal standard for LC-MS/MS testing of the immunosuppressants tacrolimus, sirolimus, and everolimus. This Certified Spiking Solution™ is suitable for critical quantitative applications in clinical and diagnostic testing such as therapeutic drug monitoring assays to ensure patients remain within the narrow therapeutic range of these immunosuppressants.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ascomycin is a potent immunosuppressive agent that could be used as a potential therapeutic agent for autoimmune diseases. Ascomycin is an inhibitor of PP2. It is an internal standard for LC-MS/MS testing of the immunosuppressants tacrolimus, sirolimus, and everolimus. This Certified Spiking Solution® is suitable for critical quantitative applications in clinical and diagnostic testing such as therapeutic drug monitoring assays to ensure patients remain within the narrow therapeutic range of these immunosuppressants.

Solubility
Soluble in DMSO at 65mg/ml; soluble in ethanol at 50mg/m; with warming. Very poorly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 104987-12-4
Formula molecolare C43H69NO12
Molecular Weight (g/mol) 792.02
Numero MDL MFCD06198665
InChI Key ZDQSOHOQTUFQEM-NURRSENYSA-N
Sinonimo ascomycin, immunomycin, unii-auf4u5nsjk, ascomycin fk520, auf4u5nsjk, chembl8597, 15,19-epoxy-3h-pyrido 2,1-c 1,4 oxaazacyclotricosine-1,7,20,21 4h,23h-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-2-4-hydroxy-3-methoxycyclohexyl-1-methylethenyl-14,16-dimethoxy-4,10,12,18-tetram, ascomycin from streptomyces hygroscopicus var. ascomyceticus, 15,19-epoxy-3h-pyrido 2,1-c 1,4 oxaazacyclotricosine-1,7,20,21 4h,23h-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-8-ethyl-3-2-4-hydroxy-3-methoxycyclohexyl-1-methylethenyl-14,16-dimethoxy-4,10,12,18-tetramethyl-, 3s-3r* e 1s*,3s*,4s* ,4s*,19s*,26ar*, ascomycin fk 520, fr 900520, imm
PubChem CID 5282071
ChEBI CHEBI:29582
SMILES CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC)C)C

Specifica

Materiale o nome chimico Ascomycin
Punto di fusione 156°C to 160°C
Punti di ebollizione 868°C
Punto d'infiammabilità >110°C (230°F)
Imballaggio Plastic bottle
Quantità 100 mg
Informazioni di solubilità Soluble in DMSO at 65mg/ml; soluble in ethanol at 50mg/m; with warming. Very poorly soluble in water
Peso formulazione 790
Percent Purity 95%
Forma fisica Powder

RUO – Research Use Only

Titolo del prodotto
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