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ATR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Specifica
Antigene | ATR |
---|---|
Concentrazione | 0.28 mg/mL |
Applicazioni | Immunohistochemistry (Paraffin), Western Blot |
Classificazione | Polyclonal |
Coniugato | Unconjugated |
Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
---|---|---|---|---|---|---|---|---|---|
Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
16899264
|
Proteintech
19787-1-AP-20UL |
20 μL |
140.00€
20µL |
Spedizione stimata: 08-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
16889264
|
Proteintech
19787-1-AP-150UL |
150 μL |
399.00€
150µL |
Spedizione stimata: 08-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
Descrizione
The antibody can recognize all the isoform of ATR.
The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin. Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF). This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis.Specifica
ATR | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q13535, Q9JKK8 | |
245000, 545, 685055 | |
Peptide | |
Primary | |
-20°C | |
ATR |
0.28 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
ATR, FRAP related protein 1, FRP1, MEC1, SCKL, SCKL1 | |
ATR | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |