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Thermo Scientific Chemicals Aurora Kinase/Cdk Inhibitor

Codice prodotto. 15447179
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Quantità:
5 mg
Dimensione della confezione:
5mg
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15447179 5 mg 5mg
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Codice prodotto. 15447179 Fornitore Thermo Scientific Chemicals N. del fornitore J65997.#0
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Descrizione

 

Aurora Kinase/Cdk Inhibitor is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. It as been shown to induce growth suppression and mitotic defects, these results suggest that Aurora Kinase/Cdk Inhibitor could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

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Specifica

Quantità 5 mg
Descrizione White
Content And Storage 2°C to 8°C
Da utilizzare con (applicazione) A cell-permeable triazolylsulfonamido compound that acts a reversible, ATP-competitive kinase inhibitor with selectivities towards Aurora kinases
CAS 443797-96-4
Formula molecolare C15H12F2N6O3S.CH3CN, C15H12F2N6O3S
Peso formulazione 435.41
Sinonimo 4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide;
Sensibilità Light Sensitive
Solubilità Soluble in DMSO at 15mg/ml
Product Type Aurora Kinase/Cdk Inhibitor
Forma Powder
InChI Key KDKUVYLMPJIGKA-UHFFFAOYSA-N
SMILES NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F
IUPAC Name 4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide
Molecular Weight (g/mol) 394.36
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RUO – Research Use Only

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