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Invitrogen™ B-Raf (V600E) Recombinant Rabbit Monoclonal Antibody (RM8)
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Codice prodotto. 15885873
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità unitSize
15885873 100 μg 100µg
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Codice prodotto. 15885873 Fornitore Invitrogen™ N. del fornitore MA524661

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404.60 EUR valido fino al 2026-05-15
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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
To receive the discount customers must purchase 2 of the same product at list price in a single order to receive 30% discount. There is no limit to the multiples of 2 that customers can buy. Use promo code ”27974” to get your promotional price

Descrizione

Rabbit Recombinant Monoclonal Antibody

This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene, B-RAF/BRAF, encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome.
TRUSTED_SUSTAINABILITY

Specifica

Antigene B-Raf (V600E)
Applicazioni ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classificazione Recombinant Monoclonal
Clone RM8
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 50% glycerol, 1% BSA and 0.09% sodium azide; pH 7.2-7.4
Gene BRAF
N. accesso geni P15056
Alias gene 94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1
Simboli geni BRAF
Specie ospite Rabbit
Immunogeno Peptide corresponding to B-Raf V600E mutant.
Metodo di purificazione Protein A
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 673
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Forma Liquid
Isotype IgG
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