missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Descrizione
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
Specifica
Specifica
| Antigene | BBS9 |
| Applicazioni | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Classificazione | Polyclonal |
| Concentrazione | 0.37 mg/mL |
| Coniugato | Unconjugated |
| Formulazione | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | BBS9 |
| N. accesso geni | Q3SYG4, Q811G0 |
| Alias gene | B1, Bardet Biedl syndrome 9, BBS9, C18, D1, Protein PTHB1, PTHB1 |
| Simboli geni | BBS9 |
| Vedi altri risultati |
Titolo del prodotto
Facendo clic su Invia, l'utente riconosce che potrebbe essere contattato da Fisher Scientific in merito al feedback fornito in questo modulo. Non condivideremo le vostre informazioni per altri scopi. Tutte le informazioni di contatto fornite saranno conservate in conformità con la nostra Politica sulla privacy. Informativa sulla privacy.
Individuate un'opportunità di miglioramento?