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Berberine chloride

Codice prodotto. 15424719
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Quantità:
5 g
Dimensione della confezione:
5g
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Codice prodotto. Quantità Dimensione della confezione
15424719 5 g 5g
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Codice prodotto. 15424719 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J62311.06
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Descrizione

CAS: 633-65-8 | C20H18ClNO4 | 371.817 g/mol

Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dimethyl sulfoxide (74 mg/ml at 25°C), ethanol (<1mg/mL at 25°C), water (<1mg/mL at 25°C), and methanol.

Notes
Store at -20°C. Incompatible with oxidizing agents. Protect from heat.
TRUSTED_SUSTAINABILITY

Specifica

Materiale o nome chimico Berberine chloride
CAS 633-65-8
Colore Yellow to Orange
Formula molecolare C20H18ClNO4
Numero MDL MFCD00011939
Quantità 5 g
Beilstein 3836585
Sinonimo berberine chloride, berberine hydrochloride, natural yellow 18, benzodioxide, berberinium chloride, berberine hcl, unii-uot4o1byv8, berberine chloride jan, uot4o1byv8
Informazioni di solubilità Soluble in dimethyl sulfoxide (74mg/ml at 25°C),ethanol (<1mg/ml at 25°C),water (<1mg/ml at 25°C),and methanol.
InChI Key VKJGBAJNNALVAV-UHFFFAOYSA-M
SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]
Molecular Weight (g/mol) 371.817
PubChem CID 12456
ChEBI CHEBI:31271
Peso formulazione 371.82
Forma fisica Powder
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