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beta 2-Microglobulin Antibody (B2M/961), Novus Biologicals™

Codice prodotto. 18112158 Sfoglia Tutto Bio Techne Prodotti
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Codice prodotto. Quantità unitSize
18112158 0.02 mg 0.02mg
18757903 0.1 mg 0.10mg
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Codice prodotto. 18112158 Fornitore Novus Biologicals N. del fornitore NBP2444710.02MG

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Descrizione

Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Cell Surface).
TRUSTED_SUSTAINABILITY

Specifica

Antigene beta 2-Microglobulin
Applicazioni Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classificazione Monoclonal
Clone B2M/961
Concentrazione 0.2mg/mL
Coniugato Unconjugated
Diluizione Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Formulazione 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
N. accesso geni P61769
Alias gene beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Simboli geni B2M
Specie ospite Mouse
Immunogeno Full length recombinant human B2M protein
Peso molecolare dell'antigene 12 kDa
Metodo di purificazione Protein A or G purified
Quantità 0.02 mg
Status giuridico RUO
Disciplina di ricerca Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
Primario o secondario Primary
ID gene (immissione) 567
Test di specificità Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Target Species Human, Primate
Content And Storage Store at 4C.
Forma Purified
Isotype IgG2b κ
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For Research Use Only

Titolo del prodotto
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