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  6. beta-Estradiol, 99% (dry wt.), ca 3% water

beta-Estradiol, 99% (dry wt.), ca 3% water

Codice prodotto. 11386656
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Quantità:
1 g
5 g
25 g
Dimensione della confezione:
1g
25g
5g
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Codice prodotto. 11386656

Marca: Thermo Scientific Alfa Aesar L03801.14

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Descrizione

CAS: 50-28-2 | C18H24O2 | 272.388 g/mol

β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner's syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner′s syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

Solubility
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.

Notes
Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 50-28-2
Formula molecolare C18H24O2
Molecular Weight (g/mol) 272.388
Numero MDL MFCD00003693
InChI Key VOXZDWNPVJITMN-ZBRFXRBCSA-N
Sinonimo estradiol, beta-estradiol, 17beta-estradiol, oestradiol, dihydrofolliculin, estrace, ovocyclin, progynon, dihydrotheelin, dihydroxyestrin
PubChem CID 5757
ChEBI CHEBI:16469
IUPAC Name (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
SMILES CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O

Specifica

Materiale o nome chimico beta-Estradiol
Punto di fusione 175°C to 178°C
Note percentuale saggio (dry wt.), ≈3% water
Quantità 25 g
Beilstein 1914275
Indice di Merck 14,3703
Informazioni di solubilità Soluble in dimethyl sulfoxide,ethanol ,water,phosphate buffer saline,dimethyl formamide,acetone,dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Optical Rotation +79° (c=1 in Dioxane)
Peso formulazione 272.39
Percent Purity 99%

RUO – Research Use Only

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