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  7. Bexarotene, 98%, Thermo Scientific Chemicals

Bexarotene, 98%, Thermo Scientific Chemicals

Codice prodotto. 15485879
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Quantità:
100 mg
Dimensione della confezione:
100mg
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15485879 100 mg 100mg
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Codice prodotto. 15485879 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J63701.MC
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Descrizione

Synthetic retinoid analog with specific affinity for the retinoid X receptor

Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer's model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Solubility
Soluble in DMSO and ethanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 153559-49-0
Formula molecolare C24H28O2
Molecular Weight (g/mol) 348.49
Numero MDL MFCD00932428
InChI Key NAVMQTYZDKMPEU-UHFFFAOYSA-N
Sinonimo bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
PubChem CID 82146
ChEBI CHEBI:50859
IUPAC Name 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
SMILES CC1=CC2=C(C=C1C(=C)C1=CC=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C

Specifica

Materiale o nome chimico Bexarotene
Punto di fusione 220°C to 225°C
Colore White
Quantità 100 mg
Indice di Merck 14,1194
Informazioni di solubilità Soluble in DMSO and ethanol
Peso formulazione 348.48
Percent Purity ≥99%
Forma fisica Powder

RUO – Research Use Only

Titolo del prodotto
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