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ACROBiosystems Biotinylated Human Syndecan-1 Protein, Fc, Avitag™

Biotinylated Protein

453.47€ - 1995.26€

Specifica

Peso molecolare 52.0 kDa
Sorgente Biotinylated Human Syndecan-1, Fc,Avitag (SY1-H82F3) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).
Immunogeno Gln 23 - Gly 254
Requisiti di stoccaggio -20°C
Alias gene SDC1,Syndecan-1,CD138,SYND1,SDC
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Prodotti 2
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
Codice del prodotto Marca Quantità Prezzo Quantità e disponibilità  
17106791
Vedere i documenti Dettagli della promozione
ACROBiosystems
SY1-H82F3-200UG
200 μg
1995.26€
200µg
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Spedizione stimata: 11-04-2024
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17116791
Vedere i documenti Dettagli della promozione
ACROBiosystems
SY1-H82F3-25UG
25 μg
453.47€
25µg
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Spedizione stimata: 11-04-2024
per visualizzare lo stock disponibile
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Descrizione

Descrizione

Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 52.0 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Specifica

Specifica

52.0 kDa
Gln 23 - Gly 254
SDC1,Syndecan-1,CD138,SYND1,SDC
Precision Avi
Fc Tag and Avi Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
Biotinylated Human Syndecan-1, Fc,Avitag (SY1-H82F3) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).
-20°C
Syndecan-1
Human
PBS, pH7.4
HEK293
MABSol™ Biotin Labeled Proteins
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SDS
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