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Calumenin Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 17804-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16897784

  • 121.38€ / 20µL

Spedizione stimata: 11-10-2022
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Descrizione

Descrizione

Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and/or wound healing by acting in an autocrine or paracrine manner.
Specifica

Specifica

Calumenin
Polyclonal
Unconjugated
CALU
CALU, Calumenin, Crocalbin, IEF SSP 9302
Rabbit
Antigen Affinity Chromatography
RUO
12321, 813
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
0.46 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O35887, O43852
CALU
Calumenin Fusion Protein Ag12073
20 μL
Primary
Human, Mouse
Antibody
IgG
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