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DiscoverX cAMP Hunter™ CHO-K1 SSTR4 Gi Cell Line

Codice prodotto. 17334489
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Quantità:
2 Vials
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Codice prodotto. Quantità
17334489 2 Vials
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Codice prodotto. 17334489 Fornitore DiscoverX N. del fornitore 950059C2

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The cAMP Hunter™ CHO-K1 SSTR4 Gi Cell Line measures SSTR4 (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.

The cAMP Hunter SSTR4 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin 28) based activation of SSTR4 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype SSTR4 , a naturally Gi/Go coupled GPCR. Upon activation of SSTR4 , the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry Intracellular cAMP level
Linea cellulare CHO-K1
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Somatostatin 28
Quantità 2 Vials
Target Entry SSTR4
Numero di accesso AY548169
Titolo del prodotto
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