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Capsazepine, 98+%

Codice prodotto. 15415329
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15415329 50 mg 50mg
15405329 10 mg 10mg
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Codice prodotto. 15415329 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J63055.MF
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Spedizione stimata: 08-10-2026
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Descrizione

A competitive antagonist for capsaicin and resiniferatoxin | CAS: 138977-28-3 | C19H21ClN2O2S | 376.899 g/mol

Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

Solubility
Soluble in ethanol or DMSO

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 138977-28-3
Formula molecolare C19H21ClN2O2S
Molecular Weight (g/mol) 376.899
Numero MDL MFCD00153778
InChI Key DRCMAZOSEIMCHM-UHFFFAOYSA-N
Sinonimo capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464
PubChem CID 2733484
ChEBI CHEBI:70773
IUPAC Name N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
SMILES C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O

Specifica

Materiale o nome chimico Capsazepine
Punto di fusione 159°C to 161°C
Colore White
Quantità 50 mg
Informazioni di solubilità Soluble in ethanol or DMSO
Peso formulazione 376.9
Percent Purity ≥99%
Forma fisica Powder

RUO – Research Use Only

Titolo del prodotto
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