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Invitrogen™ Cardiac Troponin T Monoclonal Antibody (1C11cc)
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Codice prodotto. 11568293
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Quantità:
200 μg
Dimensione della confezione:
200µg
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Codice prodotto. Quantità unitSize
11568293 200 μg 200µg
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Codice prodotto. 11568293 Fornitore Invitrogen™ N. del fornitore MA116687

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Descrizione

Mouse Monoclonal Antibody

This antibody is useful for Troponin T immunoassay. This antibody will work best as a capture for BIAcore. Suggested positive control: antigen standard for TNNT2 (transient overexpression lysate).

Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Cardiac Troponin T
Applicazioni ELISA, Western Blot
Classificazione Monoclonal
Clone 1C11cc
Concentrazione 5.8 mg/mL
Coniugato Unconjugated
Formulazione PBS with 0.09% sodium azide; pH 7.4
Gene TNNT2
N. accesso geni P45379, P50752, P50753
Alias gene alternatively spliced; cardiac muscle troponin T; cardiac TnT; cardiac troponin 2; cardiac troponin 2 adult #1 isoform; cardiac troponin 2 adult #2 isoform; cardiac troponin 2 embryonic #1 isoform; cardiac troponin 2 embryonic #2 isoform; cardiac troponin 2, exclusion exon 6 #1 isoform; cardiac troponin 2, exclusion exon 6 #2 isoform; cardiac troponin T; cardiac troponin T form I; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T isoform I; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; CMD1D; CMH2; CMPD2; cTnT; Ctt; CTTG; LVNC6; MGC3889; RATCTTG; RCM3; TNNT2; Tnnt3; Tnt; TnTc; troponin T; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; Troponin T, cardiac muscle isoforms; Troponin T2; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T
Simboli geni TNNT2
Specie ospite Mouse
Immunogeno Free human cTnT.
Metodo di purificazione Protein A
Quantità 200 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 21956, 24837, 403532, 7139
Target Species Canine, Human, Mouse, Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Forma Liquid
Isotype IgG1
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