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CD38 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA512509

Dettagli aggiuntivi : Peso : 0.01000kg

Codice prodotto. 10018779

  • 514.00€ / 100µg
Spedizione stimata: 26-06-2024
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Descrizione

Descrizione

This antibody is predicted to react with non-human primate based on sequence homology.

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, malignant lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter's Syndrome.
Specifica

Specifica

CD38
Polyclonal
Unconjugated
CD38
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10
Rabbit
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
952
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
1.7 mg/mL
PBS with 0.09% sodium azide
P28907
CD38
KLH conjugated synthetic peptide between 241-270 amino acids from the C-terminal region of human CD38
400 μL
Primary
Human
Antibody
IgG
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