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CD63 Antibody (SPM524), DyLight 350, Novus Biologicals™

Codice prodotto. 18183979 Sfoglia Tutto Bio Techne Prodotti
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Quantità:
0.1 mL
Dimensione della confezione:
0.10mL
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Codice prodotto. Quantità unitSize
18183979 0.1 mL 0.10mL
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Codice prodotto. 18183979 Fornitore Novus Biologicals N. del fornitore NBP234779UV

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Descrizione

Mouse Monoclonal Antibody

CD63 Monoclonal specifically detects CD63 in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifica

Antigene CD63
Applicazioni Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classificazione Monoclonal
Clone SPM524
Coniugato DyLight 350
Diluizione Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Alias gene CD63 antigen, CD63 antigen (melanoma 1 antigen), CD63 molecule, Granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, ME491, melanoma 1 antigen, Melanoma-associated antigen ME491, melanoma-associated antigen MLA1, MLA1lysosome-associated membrane glycoprotein 3, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, tspan-30, TSPAN30granulophysin
Simboli geni CD63
Specie ospite Mouse
Immunogeno Smooth plasma membrane fraction of MeWo cells
Metodo di purificazione Protein A or G purified
Quantità 0.1 mL
Status giuridico RUO
Disciplina di ricerca Autophagy, Cancer, Cardiovascular Biology, Cytokine Research, Immunology, Innate Immunity, Lysosome Markers, Metastasis
Primario o secondario Primary
ID gene (immissione) 967
Test di specificità This monoclonal antibody recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of monoclonal antibody LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Target Species Human, Mouse
Content And Storage Store at 4C in the dark.
Forma Purified
Isotype IgG1 κ
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For Research Use Only

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