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Invitrogen™ CD80 (B7-1) Monoclonal Antibody (IL-A159)
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Codice prodotto. 16362714
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità unitSize
16362714 100 μg 100µg
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Codice prodotto. 16362714 Fornitore Invitrogen™ N. del fornitore MA528445

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Mouse Monoclonal Antibody

This antibody recognizes the bovine CD80 cell surface antigen, expressed by dendritic cells, activated macrophages and activated B cells. CD80 plays a key role in co-stimulation of T cells during the primary immune response.

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
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Specifica

Antigene CD80 (B7-1)
Applicazioni Flow Cytometry
Classificazione Monoclonal
Clone IL-A159
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 0.09% sodium azide
Gene CD80
N. accesso geni 0
Alias gene Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1
Simboli geni CD80
Specie ospite Mouse
Metodo di purificazione Protein A
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 407131
Target Species Bovine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Forma Liquid
Isotype IgG1
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