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Invitrogen™ Cdc23 Polyclonal Antibody

Descrizione
A suggested positive control is K562 cell lysate. PA5-20949 can be used with blocking peptide PEP-1063.
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
Specifica
Specifica
| Antigene | Cdc23 |
| Applicazioni | Western Blot, Immunocytochemistry |
| Classificazione | Polyclonal |
| Concentrazione | 1 mg/mL |
| Coniugato | Unconjugated |
| Formulazione | PBS with 0.02% sodium azide |
| Gene | Cdc23 |
| N. accesso geni | Q8BGZ4, Q9UJX2 |
| Alias gene | 6030435O18; ANAPC8; anaphase promoting complex subunit 8; anaphase-promoting complex subunit 8; APC8; CDC23; CDC23 (cell division cycle 23, yeast, homolog); CDC23 cell division cycle 23; cell division cycle 23; cell division cycle 23 homolog; cell division cycle protein 23; cell division cycle protein 23 homolog; CUT23; cyclosome subunit 8; D18Ertd243e; zgc:56013 |
| Simboli geni | Cdc23 |
| Vedi altri risultati |
Titolo del prodotto
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