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Invitrogen™ CLOCK Polyclonal Antibody
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Codice prodotto. 11503591
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Quantità:
200 μL
Dimensione della confezione:
200µL
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Codice prodotto. Quantità unitSize
11503591 200 μL 200µL
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Codice prodotto. 11503591 Fornitore Invitrogen™ N. del fornitore PA1520

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Descrizione

Rabbit Polyclonal Antibody

PA1-520 detects CLOCK from human, mouse, rat and hamster tissues. PA1-520 has been successfully used in Western blot, ICC/IF and immunohistochemistry procedures. By Western blot, this antibody detects an ~100 kDa protein representing CLOCK from rat brain homogenate. Immunohistochemical staining of CLOCK in hamster brain with PA1-520 results in the staining of the superchiasmatic nucleus. PA1-520 immunizing peptide corresponds to amino acid residues 11-30 of mouse CLOCK. This sequence is completely conserved between mouse and human CLOCK. PA1-520 immunizing peptide (Cat. # PEP-072) is available for use in neutralization and control experiments.

This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
TRUSTED_SUSTAINABILITY

Specifica

Antigene CLOCK
Applicazioni Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 1mg/mL BSA and 0.05% sodium azide
Gene CLOCK
N. accesso geni O08785, O15516, Q9WVS9
Alias gene 5330400M04Rik; bHLHe8; circadian locomoter output cycles kaput; circadian locomoter output cycles kaput protein; circadian locomoter output cycles protein kaput; circadian locomotor output cycles kaput; class E basic helix-loop-helix protein 8; CLOCK; clock circadian regulator; clock homolog; hCLOCK; I79_020252; KAT13D; KIAA0334; mCLOCK; rCLOCK
Simboli geni CLOCK
Specie ospite Rabbit
Immunogeno Synthetic Peptide: S(11) S I V D R D D S S I F D G L V E E D D(30) C.
Metodo di purificazione Antigen affinity chromatography
Quantità 200 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 100770092, 12753, 60447, 9575
Target Species Human, Mouse, Rat, Hamster
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Forma Liquid
Isotype IgG
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