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Clotrimazole

Codice prodotto. 15496049
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Quantità:
5 g
25 g
Dimensione della confezione:
25g
5g
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15496049 25 g 25g
15486049 5 g 5g
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Codice prodotto. 15496049 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J63895.14
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Spedizione stimata: 07-10-2026
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Descrizione

Specific inhibitor of calcium-activated potassium channels | CAS: 23593-75-1 | C22H17ClN2 | 344.842 g/mol

Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.

Solubility
Soluble in chloroform, DMSO, DMF and alcohols

Notes
Store at room temperature. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 23593-75-1
Formula molecolare C22H17ClN2
Molecular Weight (g/mol) 344.842
Numero MDL MFCD00057220
InChI Key VNFPBHJOKIVQEB-UHFFFAOYSA-N
Sinonimo 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole
PubChem CID 2812
ChEBI CHEBI:3764
IUPAC Name 1-[(2-chlorophenyl)-diphenylmethyl]imidazole
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

Specifica

Materiale o nome chimico Clotrimazole
Tipo Clotrimazole
Forma fisica Powder
Punto di fusione 141°C to 149°C
Colore White
Quantità 25 g
Indice di Merck 14,2417
Informazioni di solubilità Soluble in chloroform, DMSO, DMF and alcohols
Peso formulazione 344.84

RUO – Research Use Only

Titolo del prodotto
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