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ACROBiosystems Cynomolgus Siglec-10 Protein, His Tag

Marca:  ACROBiosystems SI0-C52H5-1mg

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17106711

  • dietro preventivo / 1mg

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Descrizione

Descrizione

The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.2 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Specifica

Specifica

Powder
>95% as determined by SDS-PAGE
Cynomolgus Siglec-10, His Tag (SI0-C52H5) is expressed from human 293 cells (HEK293). It contains AA Thr 17 - Ala 549 (Accession # A0A2K5WB x 8-1).
-20°C
Siglec-10
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
60.2 kDa
1 mg
Thr 17 - Ala 549
SIGLEC10,MGC126774,PRO940,Siglec10,SLG2
Unconjugated
25 mM MES, 150 mM NaCl, pH5.5
HEK293
Cynomolgus
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