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DAPT

Codice prodotto. 15467109
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Quantità:
10 mg
Dimensione della confezione:
10mg
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Codice prodotto. Quantità Dimensione della confezione
15467109 10 mg 10mg
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Codice prodotto. 15467109 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J65864.MA
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Descripción

CAS: 208255-80-5 | C23H26F2N2O4 | 432.468 g/mol

DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth, angiogenesis, and differentiation of human induced pluripotent stem cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth,
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Especificaciones

Materiale o nome chimico DAPT
CAS 208255-80-5
Colore White
Formula molecolare C23H26F2N2O4
Numero MDL MFCD04974585
Quantità 10 mg
Sensibilità Light Sensitive
Sinonimo dapt, dapt gsi-ix, gamma-secretase inhibitor ix, gsi-ix, insolution gamma-secretase inhibitor ix, s-tert-butyl 2-s-2-2-3,5-difluorophenyl acetamido propanamido-2-phenylacetate, n-n-3,5-difluorophenacetyl-l-alanyl-s-phenylglycine t-butyl ester, tert-butyl 2s-2-2s-2-2-3,5-difluorophenyl acetamido propanamido-2-phenylacetate, tert-butyl 2s-2-2s-2-2-3,5-difluorophenyl acetyl amino propanoyl amino-2-phenylacetate, gsiix
Informazioni di solubilità Soluble in DMSO,ethanol,dichloromethane,DMF.
InChI Key DWJXYEABWRJFSP-XOBRGWDASA-N
SMILES CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F
IUPAC Name tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
Molecular Weight (g/mol) 432.468
PubChem CID 5311272
ChEBI CHEBI:86193
Peso formulazione 432.5
Forma fisica Lyophilized
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RUO – Research Use Only

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