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  6. Deoxycholic acid, sodium salt, 99%, extra pure, Thermo Scientific Chemicals

Deoxycholic acid, sodium salt, 99%, extra pure, Thermo Scientific Chemicals

Catalog Number 10104560
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Quantità:
25 g
100 g
500 g
Imballaggio:
Glass bottle
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302-95-4
C24H39NaO4
414.56
MFCD00064139
FHHPUSMSKHSNKW-SMOYURAASA-M
sodium deoxycholate
91810855
[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Request Bulk Custom & GMP Chemicals
302-95-4
C24H39NaO4
414.56
MFCD00064139
FHHPUSMSKHSNKW-SMOYURAASA-M
sodium deoxycholate
91810855
[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

Descrizione

Deoxycholic acid, sodium salt, CAS # 302-95-4, also designed as sodium deoxycholate, is a biological anionic bile acid detergent that is especially useful for disrupting and dissociating protein interactions.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • The deoxycholic acid sodium salt is a bile acid choleretic and anionic detergent that allows the solubilization of fats for intestinal absorption
  • The compound is an intermediate in the production of corticosteroids
  • In animal models it has been shown that this compound can promote tyrosine phosphorylation of β-catenin and its translocation to the nucleus, promoting the activation of β-catenin signaling


Applications

  • Deoxycholic acid is mainly useful for the extraction of membrane receptors, other plasma membrane proteins, nuclei isolation, solubilization and isolation of fats, and some components of biological membranes (in an active state)
  • It has been used for chemical applications, mainly for the elution or regeneration of specific types of affinity columns. Furthermore, this compound can be used to prevent non-specific binding in affinity chromatography.
  • It has been applied in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins
  • Deoxycholic acid, sodium salt is also recommended for stripping endotoxins
TRUSTED_SUSTAINABILITY
Materiale o nome chimico Deoxycholic acid, sodium salt
Colore White to Cream
pH 7.5 to 10 (5% aq. soln.)
Perdita all'essiccatura 5% max. (2 g, 105°C, 4 hrs)
Spettro a infrarossi Authentic
Intervallo percentuale saggio 99%
Imballaggio Glass bottle
Quantità 25 g
Beilstein 10, III, 1642
Indice di Merck 14, 2899
Rotazione specifica +42° to +46° (20°C, 589nm) (c=2, water)
IUPAC Name sodium;(4R)-4-[(3R,5R,8R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
Peso formulazione 414.58
Percent Purity 98.5 to 102% (on dry substance)
Grado Extra Pure
Forma fisica Crystalline Powder
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Sicurezza e movimentazione

compliance-icons
Identificativo prodotto
  • Deoxycholic acid, sodium salt
 Avvertenza
  • Attenzione
 Categoria di pericolo
  • Tossicità acuta Categoria 4
  • Tossicità specifica per organi bersaglio (esposizione singola) Categoria 3
 Indicazioni di pericolo
  • H335-Può irritare le vie respiratorie.
  • H302-Nocivo se ingerito.
 Consigli di prudenza
  • P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
  • P264-Lavare accuratamente dopo l'uso.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P312-Contattare un CENTRO ANTIVELENI/un medico/in caso di malessere.

RUO – Research Use Only

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