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Dexamethasone, 96%, Thermo Scientific Chemicals

Codice prodotto. 10053130 Sfoglia Tutto Thermo Scientific Chemicals Prodotti
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Quantità:
250 mg
1 g
5 g
Imballaggio:
Bottiglia in vetro
Dimensione della confezione:
1g
250mg
5g
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10053130 250 mg Bottiglia in vetro 250mg
10502631 1 g Bottiglia in vetro 1g
10434225 5 g Bottiglia in vetro 5g
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Product Code. 10053130 missing translation for 'mfr' Thermo Scientific Acros missing translation for 'supplierNo' 230302500
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Description

Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways

Applications

• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 50-02-2
Formula molecolare C22H29FO5
Molecular Weight (g/mol) 392.47
Numero MDL MFCD00064136
InChI Key UREBDLICKHMUKA-CXSFZGCWSA-N
Sinonimo dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
PubChem CID 5743
ChEBI CHEBI:41879
SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

Specifications

Materiale o nome chimico Dexamethasone
Punto di fusione 255.0°C to 261.0°C
Colore White
Perdita all'essiccatura 0.5% max. (105°C, 3 hrs)
Spettro a infrarossi Authentic
Intervallo percentuale saggio 96%
Imballaggio Bottiglia in vetro
Quantità 250 mg
Indice di Merck 15, 2945
Rotazione specifica + 75.00
Informazioni di solubilità Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform
Spettrofotometria 95% min. (on dried substance)
IUPAC Name (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Peso formulazione 392.46
Percent Purity 96%
Sostanze correlate (HPLC) Passes test
Forma fisica Crystalline Powder
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Safety and Handling

compliance-icons
Product Identifier
  • Dexamethasone
 Signal Word
  • Attenzione
 Hazard Category
  • cancerogenicità Categoria 2
 Hazard Statement
  • H351-Sospettato di provocare il cancro.
 Precautionary Statement
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
SDS

RUO – Research Use Only

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