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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Product Code. 15722262 Shop All MP Biomedicals Products
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Description

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution
TRUSTED_SUSTAINABILITY

Specifications

Materiale o nome chimico Dextran Sulfate Sodium Salt
Colore White
pH 5 to 7.11 (1% aqueous solution)
CAS 9011-18-1
Forma fisica Powder
Punti di ebollizione 310°C
Punto di fusione 92°C
Formula molecolare (C6H7O5)m(C6H7O5)n
Numero MDL MFCD00081551
Informazioni di solubilità Soluble in water
Quantità 25 g
InChI Key BLFLLBZGZJTVJG-UHFFFAOYSA-N
SMILES *-OC[C@H]1O[C@H](OC[C@H]2O[C@H](-*)[C@H](O[*])[C@@H](O[*])[C@@H]2O[*])[C@H](O[*])[C@@H](O-*)[C@@H]1O[*]
IUPAC Name Dextran sulfate sodium salt
Molecular Weight (g/mol) 40,000
Da utilizzare con (applicazione) Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
Grado Colitis Grade
Moisture <10%
Imballaggio Plastic Container
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Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.

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