missing translation for 'onlineSavingsMsg'
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Descrizione
Diacylglycerol (DAG) influences numerous cell signaling cascades by functioning as an intracellular, allosteric activator of protein kinase C (PKC), and as a potent activator of guanine nucleotide exchange factors. In order to maintain cellular homeostasis, intracellular DAG levels are tightly regulated by diacylglycerol kinases (DGKs, DAGKs), which phosphorylate DAG to phosphatidic acid, thus removing DAG. Human DGK-alpha (80 kDa), -beta (90 kDa), and - gamma (90 kDa) have calcium-binding EF-hand motifs at their N termini and are classified as type I DGKs. Human DGK- delta (130 kDa) and DGK-i (130 kDa) contain N-terminal pleckstrin homology (PH) domains and are classified as type II. Human DGK- epsilon (64 kDa) contains no identifiable regulatory domains and is classified as a type III DGK. Human DGK- zeta (104 kDa) and -iota (130 kDa) possess C-terminal ankyrin repeats and are classified as type IV DGKs. Human DGK-theta (110 kDa) contains 3 cysteine-rich domains and a PH domain and is classified as a type V DGK.
Specifica
Specifica
| Antigene | DGKE |
| Applicazioni | Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence |
| Classificazione | Polyclonal |
| Concentrazione | 0.33 mg/mL |
| Coniugato | Unconjugated |
| Formulazione | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | DGKE |
| N. accesso geni | P52429, Q9R1C6 |
| Alias gene | DAG kinase epsilon, DAGK5, DAGK6, DGK, DGK epsilon, DGKE, Diacylglycerol kinase epsilon, Diglyceride kinase epsilon |
| Simboli geni | Dgke |
| Vedi altri risultati |
Titolo del prodotto
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