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Dobutamine hydrochloride

Codice prodotto. 15463939
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Quantità:
250 mg
1 g
Dimensione della confezione:
1g
250mg
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15463939 250 mg 250mg
15453939 1 g 1g
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Codice prodotto. 15463939 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J61333.MD
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CAS: 49745-95-1 | C18H24ClNO3 | 337.84 g/mol

Dobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1M.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.

Solubility
Soluble in water or ethanol with warming. Also soluble in methanol

Notes
Solutions oxidize readily at pH greater than 11. Protect solutions from light
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 49745-95-1
Formula molecolare C18H24ClNO3
Molecular Weight (g/mol) 337.84
Numero MDL MFCD00153795
InChI Key BQKADKWNRWCIJL-UHFFFAOYNA-N
Sinonimo dobutamine hydrochloride, dobutamine hcl, dobutrex, inotrex, dl-dobutamine hydrochloride, dobutamina clorhidrato spanish, 4-2-4-4-hydroxyphenyl butan-2-ylamino ethyl benzene-1,2-diol hydrochloride, +--4-2-3-p-hydroxyphenyl-1-methylpropyl amino ethyl pyrocatechol hydrochloride, 1,2-benzenediol, 4-2-3-4-hydroxyphenyl-1-methylpropyl amino ethyl-, hydrochloride, +-
PubChem CID 65324
ChEBI CHEBI:4671
IUPAC Name hydrogen 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol chloride
SMILES [H+].[Cl-].CC(CCC1=CC=C(O)C=C1)NCCC1=CC=C(O)C(O)=C1

Specifica

Materiale o nome chimico Dobutamine hydrochloride
Punto di fusione 184°C to 186°C
Colore White
Quantità 250 mg
Indice di Merck 14,3395
Informazioni di solubilità Soluble in water or ethanol with warming; Also soluble in methanol
Peso formulazione 337.85
Forma fisica Powder

RUO – Research Use Only

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