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Doxepin hydrochloride
Descrizione
It is a highly potent H1 histamine receptor antagonist (Kd = 310 pM) and tricyclic antidepressant that inhibits the reuptake of serotonin and norepinephrine and acts as an antagonist at histamine, serotonin, adrenergic, and muscarinic receptors with Ki values in the nanomolar range. Also binds to the H4 histamine receptor (pKi = 6.79). Used clinically to treat anxiety and depression.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Soluble in water (100 mM), chloroform (1:2), alcohol (1:1), methanol, and DMSO.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifica
Specifica
| Materiale o nome chimico | Doxepin hydrochloride |
| Punto di fusione | 187°C to 189°C |
| Colore | White |
| Quantità | 1 g |
| Numero UN | UN2811 |
| Indice di Merck | 14,3435 |
| Informazioni di solubilità | Soluble in water (100 mM),chloroform (1:2),alcohol (1:1),methanol,and DMSO. |
| Peso formulazione | 315.84 |
| Forma fisica | Powder |
RUO – Research Use Only
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