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DR3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 55397-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16896855

  • 121.38€ / 20µL

Spedizione stimata: 06-10-2022
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Descrizione

Descrizione

This antibody can recognize all the isoform of TNFRSF25.

DR3/TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of DR3/TNFRSF25 in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predomitly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation.
Specifica

Specifica

DR3
Polyclonal
Unconjugated
TNFRSF25
APO 3, APO3, DDR3, Death receptor 3, DR3, LARD, Protein WSL, Protein WSL 1, TNFRSF12, TNFRSF25, TR3, TRAMP, WSL, WSL 1, WSL LR, WSL1
Rabbit
Antigen Affinity Chromatography
RUO
85030, 8718
-20°C
Liquid
Western Blot
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q93038
Tnfrsf25
Peptide
20 μL
Primary
Human, Mouse
Antibody
IgG
Videos
SDS
Documenti
Certificati
Offerte speciali

Offerte speciali