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Etoposide, Thermo Scientific™

Topoisomerase inhibitor and inducer of apoptosis

Marca:  Thermo Scientific Alfa Aesar J63651.MC


Quantità 100mg

 vedi altre versioni di questo prodotto

Codice prodotto. 15405829

  • 207.00€ / 100mg

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Descrizione

Descrizione

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Etoposide is used as a inhibits DNA synthesis and is very active against cells in the late S and G2 phases of the cell cycle. Etoposide was reported to be used to serum starve Saos-2 M5(p53-/-) cells which were transfected by electroporation with indicated expression plasmids for flag-E2F1 and myc-EBNA3C for selection of colony forming units, thus studying the blocking effect of EBV Nuclear Antigen 3C on E2F1 Mediated Apoptosis Induced by the DNA Damage Response.

Solubility
Insoluble in water.

Notes
Store solutions in DMSO at 4°C. For long term storage prepare aliquots and store at -20°C.
TRUSTED_SUSTAINABILITY
Specifica

Identificatori chimici

33419-42-0
588.56
VJJPUSNTGOMMGY-MRVIYFEKSA-N
50936917
COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
C29H32O13
MFCD00869325,MFCD00869325
vjjpusntgommgy-nzlmilqcsa
(10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1,3(7),8-trien-12-one

Specifica

Etoposide
C29H32O13
100mg
vjjpusntgommgy-nzlmilqcsa
VJJPUSNTGOMMGY-MRVIYFEKSA-N
COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
588.56
588.56
33419-42-0
MFCD00869325,MFCD00869325
14,3886
Insoluble in water.
−107° (c=1 in Methanol/Dichloromethane 1:9)
(10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1,3(7),8-trien-12-one
50936917
Produktförslag

Produktförslag

Filmer
Säkerhet och hantering

Säkerhet och hantering

Produktbeteckning
  • Etoposide

Signalord
  • Pericolo

Riskkategorier
  • Tossicità acuta Categoria 4
  • cancerogenicità Categoria 1A

Faroangivelser
  • H302-Nocivo se ingerito.
  • H350-Può provocare il cancro.

Skyddsangivelse
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P264-Lavare accuratamente dopo l'uso.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
  • P312-Contattare un CENTRO ANTIVELENI/un medico/in caso di malessere.

Kompletterande information
  • MIXTURE LIST-Contain: Etoposide

SDS Dokument

Dokument

Produktspecifikationer
Kampanjer

Kampanjer

Produkttitel
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