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Factor XII Mouse anti-Human, Clone: 2E2F11, Proteintech
Mouse Monoclonal Antibody
140.00€ - 399.00€
Specifica
Antigene | Factor XII |
---|---|
Clone | 2E2F11 |
Concentrazione | 1.28 mg/mL |
Applicazioni | Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry |
Classificazione | Monoclonal |
Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
---|---|---|---|---|---|---|---|---|---|
Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
16897645
|
Proteintech
66089-1-IG-20UL |
20 μL |
140.00€
20µL |
Spedizione stimata: 09-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
16887645
|
Proteintech
66089-1-IG-150UL |
150 μL |
399.00€
150µL |
Spedizione stimata: 09-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
Descrizione
This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.Specifica
Factor XII | |
1.28 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Factor XII, Coagulation factor XII, F12, HAE3, HAEX, HAF, Hageman factor | |
F12 | |
IgG2b | |
Protein A | |
Antibody |
2E2F11 | |
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry | |
Unconjugated | |
Mouse | |
Human | |
P00748 | |
2161 | |
Factor XII Fusion Protein Ag3401 | |
Primary | |
-20°C | |
F12 |